Nobel Prize jewelry 2025

The Nobel Prize in Physiology or Medicine in 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance”.

They are awarded for their work on the FOXP3 gene (which codes for the protein foxp3), regulatory T cells and the regulation of the immune system.

Nobel prize jewelry shows the three dimensional structure of foxp3 in silver 925. A small protein, just over 80 amino acids, with four small helices and a beta hairpin.

The Nobel Prize in Physics in 2025 was awarded to John Clarke, Michel H. Devoret and John M. Martinis “for the discovery of macroscopic quantum mechanical tunnelling and energy quantisation in an electric circuit”

Quantum mechanics allows a particle to move straight through a barrier, using a process called tunnelling. Tunneling can be likened to throwing a ball against a wall and instead of bouncing, it goes through, a quantum mechanical process. If you pass current through a particular superconductor, the current can jump to the next conductor with quantum mechanical help.

This year's Nobel Prize jewel has 'captured' the tunneling step, when the ball goes through the wall. (A silver ball in a hole in the silver plate.)

The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar Yaghi “for the development of metal–organic frameworks”.

The Nobel Prize laureates have created molecular constructions with large spaces through which gases and other chemicals can flow.

One of the Nobel laureates, Richard Robson, was inspired by the structure of diamond, where each carbon atom is connected to four other carbon atoms in a pyramid-like shape. His goal was to build a similar structure. Instead of carbon, he used copper ions and a four-armed molecule with a nitrile at the end. Nitrile is a chemical group that is attracted to copper ions. When the four-armed molecule, 4′,4″,4‴,4⁗-tetracyanotetraphenylmethane, was mixed with copper, a regular and very airy crystal formed. 

This year's Nobel Prize jewel shows the three-dimensional structure of 4′,4″,4‴,4⁗-tetracyanotetraphenylmethane in silver wire with the copper ions as silver spheres.