Nobel Prize jewelry 2024

The Nobel Prize in Physiology or Medicine in 2024 was awarded to Victor Ambros and Gary Ruvkun ”for the discovery of microRNA and its role in post-transcriptional gene regulation”.

They are awarded for the discovery of a fundamental principle of how gene activity is regulated. They discovered that microRNAs, a new class of very small RNA molecules, play a crucial role. A microRNA from the lin-4 gene was shown to be complementary to sequences in a lin-14 mRNA.

Nobel prize jewelry is lin-4 mikroRNA/lin14-mRNA in silver 925 where each bead corresponds to one nucleotide.

The Nobel Prize in Physics in 2024 was awarded to John J. Hopfield and Geoffrey Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks”

They have develop methods that are the foundation of today’s powerful machine learning. John Hopfield’s associative memory is built so that all the nodes are connected to each other. Information is fed in and read out from all the nodes

Nobel prize jewelry is a Hopfield network containing 4 nodes where all are connected to each others.

The Nobel Prize in Chemistry 2024 was awarded to David Baker “for computational protein design”, Demis Hassabis and John Jumper “for protein structure prediction”.

They are awarded partly for the discovery of being able to build de novo designed proteins, partly for achieving the dream of being able to predict the structure of proteins based on the amino acid sequence.

Nobel prize jewelry is three dimensional structure of Top7 in silver 925. David Baker designed the first de novo protein, Top7. It was completely unlike any known protein. As a protein crystallographer, it feels good to be able to shape a protein as this year's Nobel prize in chemistry.